Description

Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylcarbamate CAS NO 1218790-32-9 is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial advanced pharmaceutical intermediate and Suzuki-Miyaura cross-coupling reagent for constructing complex molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Cross-Coupling Reactions: Essential reagent in Suzuki-Miyaura cross-coupling for the formation of carbon-carbon bonds between aryl or heteroaryl groups.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides.
• Material Science: Precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology: Tool compound for proteolysis-targeting chimeras (PROTACs) and other bifunctional molecule synthesis.
• Academic & Contract Research: Serves as a versatile starting material for novel organic synthesis and methodology development in R&D laboratories.

Basic Information

Product Name	Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylcarbamate
CAS No.	1218790-32-9
Molecular Formula	C20H25BN2O4
Molecular Weight	368.24 g/mol
Synonyms	Benzyl N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate; 2-Pyridinecarbamic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, phenylmethyl ester; Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-2-pyridinylcarbamate; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylcarbamic acid benzyl ester; CAS 1218790-32-9
EINECS	Contact for details

Quality Control

Our Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylcarbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when appropriate to maintain stability and purity. Keep container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.