Description

2-(3-Methoxy-4,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific biaryl motifs for enhanced activity.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the research and production of novel ligands and organometallic catalysts for transition metal-catalyzed reactions.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures via palladium-catalyzed cross-coupling.
• Fine Chemical Production: Integral to the custom synthesis of specialty and performance chemicals where precise aromatic coupling is required.

Basic Information

Product Name	2-(3-Methoxy-4,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1218790-19-2
Molecular Formula	C₁₇H₂₇BO₃
Molecular Weight	290.21 g/mol
Synonyms	(3-Methoxy-4,5-dimethylphenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[3-methoxy-4,5-dimethylphenyl]-1,3,2-dioxaborolane; Pinacol (3-Methoxy-4,5-dimethylphenyl)boronate; 3-Methoxy-4,5-dimethylbenzeneboronic acid pinacol ester; 2-(3-Methoxy-4,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(3-Methoxy-4,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Every batch of our 2-(3-Methoxy-4,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency, with comprehensive testing performed using advanced analytical techniques including NMR, HPLC, and GC. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.