Description

Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Ylcarbamate CAS NO 1218790-11-4 is a high-purity, synthetically valuable boronic ester derivative used as a key building block in modern organic synthesis. This compound is specifically designed for advanced cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is an essential intermediate for research and development chemists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used to create complex heterocyclic compounds for developing new pesticides, herbicides, and fungicides.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Employed in the synthesis of bioconjugates, probes, and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: A versatile reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.
• Custom Synthesis: Provides a foundational structure for contract manufacturing organizations (CMOs) to build bespoke, high-value compounds for clients.

Basic Information

Product Name	Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Ylcarbamate
CAS No.	1218790-11-4
Molecular Formula	C20H25BN2O4
Molecular Weight	368.24 g/mol
Synonyms	Benzyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate (common misnomer); 3-(((Benzyloxy)carbonyl)amino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Benzyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)carbamate; 5-(Boc-Amino)-3-pyridineboronic acid pinacol ester (incorrect but used); 3-N-CBz-Amino-5-boronic acid pinacol ester pyridine; CAS 1218790-11-4; Pyridine-3-carbamic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, benzyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.