Description

n-(Furan-2-Ylmethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidin-2-Amine is a high-value, multifunctional chemical building block featuring both a pyrimidine core and a boronic ester pinacol group. This compound matters for its critical role as a key intermediate in modern synthetic chemistry, enabling efficient cross-coupling reactions like the Suzuki-Miyaura reaction. Pharmaceutical and agrochemical R&D teams need it for constructing complex molecular architectures, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates containing heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific pyrimidine-based structures.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura cross-coupling to form carbon-carbon bonds, a fundamental step in constructing complex organic molecules.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and bio-conjugates for studying biological processes.
• Ligand & Catalyst Development: Acts as a precursor for creating novel ligands or organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	n-(Furan-2-Ylmethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidin-2-Amine
CAS No.	1218790-00-1
Molecular Formula	C₁₉H₂₆BN₃O₃
Molecular Weight	355.24 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(furan-2-ylmethyl)pyrimidin-2-amine; 2-Pyrimidinamine, N-[(2-furanyl)methyl]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(furfuryl)pyrimidin-2-amine; N-(Furfuryl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine; 1218790-00-1; Boronic acid, B-[2-[[(2-furanylmethyl)amino]pyrimidin-5-yl]-, 1,1-dimethylethyl ester; 5-(Pinacolatoboryl)-N-(furan-2-ylmethyl)pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our n-(Furan-2-Ylmethyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.