Description

2-(Aminocarbonylmethyl)Phenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative designed for advanced synthetic applications. This compound is a crucial building block in modern organic synthesis, offering enhanced stability and reactivity control compared to its free boronic acid counterpart. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures via cross-coupling reactions.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the formation of carbon-carbon bonds, essential in pharmaceutical intermediate synthesis.
• Pharmaceutical Research & Development: Serves as a protected boronic ester precursor for creating active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Material Science: A building block for synthesizing organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for diagnostic and research applications.
• Process Chemistry & Scale-up: The pinacol ester group provides improved handling and shelf-life, making it suitable for pilot plant and manufacturing-scale processes.

Basic Information

Product Name	2-(Aminocarbonylmethyl)Phenylboronic Acid, Pinacol Ester
CAS No.	1218789-98-0
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	2-(Aminocarbonylmethyl)benzeneboronic Acid Pinacol Ester; 2-(Carbamoylmethyl)phenylboronic Acid Pinacol Ester; [2-(Aminocarbonylmethyl)phenyl]boronic Acid Pinacol Ester; N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)formamide; 2-Formamidomethylphenylboronic Acid Pinacol Ester; B-[2-(Aminocarbonylmethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of 2-(Aminocarbonylmethyl)Phenylboronic Acid, Pinacol Ester is manufactured and tested under strict quality management protocols to ensure consistency and reliability for critical research and development work. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.