Description

2-(3-Butoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester intermediate essential for modern synthetic chemistry. This compound matters for its critical role as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional polymers, relying on its consistent reactivity and purity for successful scale-up and process optimization.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Serves as a protected boronic acid precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection agents, such as herbicides and fungicides with specific targeting properties.
• Material Science & OLED Development: Employed in the production of organic light-emitting diode (OLED) materials and other functional polymers requiring precise aromatic coupling.
• Chemical Research & Process Development: A valuable tool for medicinal and process chemists in academic and industrial R&D settings for route scouting and optimization.
• Ligand and Catalyst Preparation: Can be utilized in the synthesis of specialized ligands for catalysis or as a component in metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(3-Butoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1218789-82-2
Molecular Formula	C₁₇H₂₇BO₃
Molecular Weight	290.21 g/mol
Synonyms	3-Butoxy-5-methylbenzeneboronic acid pinacol ester; (3-Butoxy-5-methylphenyl)boronic acid pinacol ester; 2-(3-Butoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3-butoxy-5-methylphenyl)boronate; 3-Methyl-5-butoxyphenylboronic acid pinacol ester; B-(3-Butoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(3-Butoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.