Description

2-(3-(Cyclopropylmethoxy)-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl bond formations.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	2-(3-(Cyclopropylmethoxy)-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1218789-80-0
Molecular Formula	C19H29BO3
Molecular Weight	316.25 g/mol
Synonyms	[3-(Cyclopropylmethoxy)-5-methylphenyl]boronic acid pinacol ester; 2-[3-(Cyclopropylmethoxy)-5-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-(Cyclopropylmethoxy)-5-methylphenyl)boronic acid pinacol ester; Pinacol [3-(cyclopropylmethoxy)-5-methylphenyl]boronate; 3-(Cyclopropylmethoxy)-5-methylbenzeneboronic acid pinacol ester; CPM-MP-Bpin (common abbreviation); 1218789-80-0 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of our 2-(3-(Cyclopropylmethoxy)-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is produced and tested under strict quality management systems. We ensure compliance with the high-purity standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profile is provided with each shipment to guarantee reproducible performance in your critical reactions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon/nitrogen) for long-term storage and during weighing to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.