Description

3-Methyl-5-Propoxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a key Suzuki-Miyaura cross-coupling building block, enabling the efficient construction of complex biaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aryl-aryl linkages.
• Agrochemical Synthesis: Used to construct novel herbicide and fungicide molecules through palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Employed in the research and production of specialized ligands for catalysis and organometallic complexes.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Fine Chemical Manufacturing: A valuable reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	3-Methyl-5-Propoxyphenylboronic Acid, Pinacol Ester
CAS No.	1218789-73-1
Molecular Formula	C16H25BO3
Molecular Weight	276.18 g/mol
Synonyms	3-Methyl-5-propoxybenzeneboronic acid pinacol ester; 5-Propoxy-3-methylphenylboronic acid pinacol ester; (3-Methyl-5-propoxyphenyl)boronic acid pinacol ester; 2-(3-Methyl-5-propoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(3-Methyl-5-propoxyphenyl)boronic acid pinacol ester; Pinacol (3-methyl-5-propoxyphenyl)boronate
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-Propoxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.