Description

3-Ethoxy-5-Methylphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly for constructing complex aromatic and heteroaromatic systems.
• Agrochemical Synthesis: Employed in creating novel active ingredients for crop protection products, such as herbicides and fungicides.
• Material Science Research: Acts as a monomer or building block for synthesizing organic semiconductors, ligands for catalysts, and advanced polymers.
• Chemical Biology Probes: Utilized in the development of molecular probes and tools for studying biological processes.
• Process Chemistry & Scale-up: The pinacol ester protection offers enhanced stability, making it suitable for multi-step synthesis and larger-scale manufacturing processes.

Basic Information

Product Name	3-Ethoxy-5-Methylphenylboronic Acid, Pinacol Ester
CAS No.	1218789-71-9
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	(3-Ethoxy-5-methylphenyl)boronic acid pinacol ester; 5-Methyl-3-ethoxyphenylboronic acid pinacol ester; 3-Ethoxy-5-methylbenzeneboronic acid pinacol ester; Pinacol (3-ethoxy-5-methylphenyl)boronate; B-(3-Ethoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Ethoxy-5-methylphenyl-Bpin
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-5-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reproducible results in sensitive synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.