Description

Methyl 3-Butoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis, enabling the formation of complex carbon-carbon bonds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Useful for synthesizing novel boron-containing ligands for catalytic systems.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules for studying biological processes.

Basic Information

Product Name	Methyl 3-Butoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1218789-66-2
Molecular Formula	C18H27BO5
Molecular Weight	334.22 g/mol
Synonyms	3-Butoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 3-butoxy-5-(pinacolatoboryl)benzoate; 5-(Pinacolatoboraneyl)-3-butoxybenzoic acid methyl ester; Benzoic acid, 3-butoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; 1218789-66-2; Boronic acid, B-[3-(butoxy)-5-(methoxycarbonyl)phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Butoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, such as GMP intermediates and research under quality-by-design (QbD) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.