Description

3-Bromo-5-(Ethoxycarbonylmethoxy)Phenylboronic Acid, Pinacol Ester is a sophisticated organoboron building block, specifically a protected boronic acid ester, designed for advanced synthetic chemistry. Its core value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and organic photovoltaics, where controlled conjugation is critical.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Useful in constructing molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Bromo-5-(Ethoxycarbonylmethoxy)Phenylboronic Acid, Pinacol Ester
CAS No.	1218789-53-7
Molecular Formula	C₁₆H₂₂BBrO₅
Molecular Weight	385.06 g/mol
Synonyms	(3-Bromo-5-[(ethoxycarbonyl)methoxy]phenyl)boronic acid pinacol ester; 3-Bromo-5-(ethoxycarbonylmethoxy)benzeneboronic acid pinacol ester; [3-Bromo-5-(2-ethoxy-2-oxoethoxy)phenyl]boronic acid pinacol ester; B-[3-Bromo-5-[(ethoxycarbonyl)methoxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Bromo-5-(carbethoxymethoxy)phenylboronic acid pinacol ester; Pinacol [3-bromo-5-(ethoxycarbonylmethoxy)phenyl]boronate
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Ethoxycarbonylmethoxy)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (¹H, ¹³C, and ¹¹B), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep container tightly sealed under an inert atmosphere to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.