Description

Methyl 2-Amino-2-(2,3-Dichlorophenyl)Acetate CAS NO 1218646-59-3 is a high-purity, non-natural amino acid derivative characterized by its dichlorinated phenyl ring and ester functionality. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate in modern synthetic chemistry. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antimicrobial research.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging its halogenated aromatic structure.
• Peptidomimetics & Bioactive Molecule Development: Serves as a constrained amino acid analog for creating peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Research: Employed as a tool compound or precursor in probe development for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale GMP batches for clinical trials.
• Academic Research: Utilized in university and institutional labs for methodological studies in asymmetric synthesis and organocatalysis.

Basic Information

Product Name	Methyl 2-Amino-2-(2,3-Dichlorophenyl)Acetate
CAS No.	1218646-59-3
Molecular Formula	C9H9Cl2NO2
Molecular Weight	234.08 g/mol
Synonyms	Methyl (2,3-dichlorophenyl)glycinate; 2-Amino-2-(2,3-dichlorophenyl)acetic acid methyl ester; Methyl α-amino-2,3-dichlorobenzeneacetate; (2,3-Dichlorophenyl)glycine methyl ester; Methyl 2-amino-(2,3-dichlorophenyl)acetate; Methyl DL-2-amino-2-(2,3-dichlorophenyl)acetate; Amino(2,3-dichlorophenyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-2-(2,3-Dichlorophenyl)Acetate is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Chiral Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.