Description

Boc-(4S,2Rs)-2-Methylthiazolidine-4-Carboxylic Acid is a high-purity, non-natural amino acid derivative featuring a thiazolidine ring and a Boc (tert-butoxycarbonyl) protecting group. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and bioactive peptides. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a constrained, non-proteinogenic amino acid analog to introduce conformational rigidity into peptide chains for structure-activity relationship (SAR) studies.
• Chemical Biology Research: Employed in the development of enzyme inhibitors and molecular probes to study biological pathways.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Ligand Development: A precursor for creating novel ligands in catalysis and medicinal chemistry.

Basic Information

Product Name	Boc-(4S,2Rs)-2-Methylthiazolidine-4-Carboxylic Acid
CAS No.	1217546-87-6
Molecular Formula	C10H17NO4S
Molecular Weight	247.31 g/mol
Synonyms	(4S,2Rs)-2-Methyl-1-(tert-butoxycarbonyl)thiazolidine-4-carboxylic acid; (2R,4S)-1-Boc-2-methylthiazolidine-4-carboxylic acid; tert-Butyl (4S,2Rs)-2-methyl-4-carboxythiazolidine-1-carboxylate; Boc-2-Me-Thz(4S,2Rs)-OH; 1-Boc-2-methylthiazolidine-4-carboxylic acid; (4S,2R)-1-(tert-Butoxycarbonyl)-2-methylthiazolidine-4-carboxylic acid; (2R,4S)-1-(tert-Butoxycarbonyl)-2-methyl-1,3-thiazolidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our Boc-(4S,2Rs)-2-Methylthiazolidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral HPLC for enantiomeric excess, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.