Description

2-Methyl-4-(Morpholinosulfonyl)Phenylboronic Acid is a specialized organoboron compound featuring a morpholinosulfonyl substituent, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This high-purity boronic acid is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: The morpholinosulfonyl group can be utilized to modify ligand properties for transition metal catalysis.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Methyl-4-(Morpholinosulfonyl)Phenylboronic Acid
CAS No.	1217501-53-5
Molecular Formula	C11H16BNO4S
Molecular Weight	269.13 g/mol
Synonyms	4-(Morpholinosulfonyl)-2-methylbenzeneboronic acid; (4-Morpholinosulfonyl-2-methylphenyl)boronic acid; 2-Methyl-4-morpholinosulfonylbenzeneboronic acid; B-[4-(Morpholine-4-sulfonyl)-2-methylphenyl]boronic acid; 2-Methyl-4-(4-morpholinesulfonyl)phenylboronic acid; 1217501-53-5
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-4-(Morpholinosulfonyl)Phenylboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications designed for research and cGMP-grade applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.