Description

1-(tert-Butoxycarbonyl)-3-Methyl-1H-Pyrazol-5-Ylboronic Acid is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating key carbon-carbon bond-forming reactions in complex molecule assembly. It is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for target identification and validation.
• Process Chemistry & Scale-up: Provides a reliable and efficient route for the kilogram-scale production of advanced intermediates under GMP or non-GMP conditions.
• Academic Research: A valuable tool for methodology development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	1-(tert-Butoxycarbonyl)-3-Methyl-1H-Pyrazol-5-Ylboronic Acid
CAS No.	1217501-27-3
Molecular Formula	C9H15BN2O4
Molecular Weight	226.04 g/mol
Synonyms	3-Methyl-1-Boc-1H-pyrazol-5-ylboronic acid; 1-Boc-3-methyl-1H-pyrazol-5-ylboronic acid; 1-(tert-Butoxycarbonyl)-3-methyl-1H-pyrazol-5-ylboronic acid; 5-Borono-3-methyl-1-(tert-butoxycarbonyl)-1H-pyrazole; 1H-Pyrazole-5-boronic acid, 1-(1,1-dimethylethoxy)carbonyl-3-methyl-; B-[1-[(tert-Butoxy)carbonyl]-3-methyl-1H-pyrazol-5-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)-3-Methyl-1H-Pyrazol-5-Ylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material for research use under quality systems appropriate for your development phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.