Description

2-Borono-5-Fluorobenzamide is a high-purity boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing fluorinated drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides with enhanced efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials and liquid crystals where fluorine substitution is desired.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and enzyme inhibitors that utilize boronic acid chemistry for binding and sensing applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring specific fluorinated boronic acid components.

Basic Information

Product Name	2-Borono-5-Fluorobenzamide
CAS No.	1217500-90-7
Molecular Formula	C7H7BFNO2
Molecular Weight	166.95 g/mol
Synonyms	5-Fluoro-2-carbamoylphenylboronic acid; (5-Fluoro-2-carbamoylphenyl)boronic acid; 2-Carbamoyl-5-fluorophenylboronic acid; 2-Aminocarbonyl-5-fluorobenzeneboronic acid; 5-Fluoro-2-boronobenzamide; B-(5-Fluoro-2-carbamoylphenyl)boronic acid; 1217500-90-7
EINECS	Contact for details

Quality Control

Every batch of 2-Borono-5-Fluorobenzamide is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity (typically ≥95% by HPLC), and impurity profiles. Our quality protocols are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.