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5-Acrylamido-2-((Dimethylamino)Methyl)Phenylboronic Acid CAS NO 1217500-78-1


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CAS No.:1217500-78-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Acrylamido-2-((Dimethylamino)Methyl)Phenylboronic Acid is a sophisticated, multi-functional boronic acid derivative designed for advanced organic synthesis and materials science. This compound is engineered to serve as a key building block in the development of novel polymers, sensors, and pharmaceutical intermediates, offering unique reactivity due to its combined acrylamide, tertiary amine, and boronic acid functionalities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to create innovative, high-value products.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of targeted drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
  • Polymer Science & Smart Materials: Serves as a functional monomer for creating stimuli-responsive (pH or glucose-sensitive) hydrogels and advanced polymeric networks.
  • Chemical Biology & Bioconjugation: Used in the development of probes, sensors, and affinity ligands that leverage boronic acid-diol interactions for detecting sugars or labeling biomolecules.
  • Agrochemical Research: Employed in the design and synthesis of novel active ingredients with specific targeting properties.
  • Organic Synthesis Building Block: Facilitates Suzuki-Miyaura cross-coupling reactions and serves as a versatile handle for further chemical modifications.
  • Diagnostic Assay Development: Potential use in the fabrication of biosensors and diagnostic strips for clinical or environmental monitoring.

Basic Information

Product Name 5-Acrylamido-2-((Dimethylamino)Methyl)Phenylboronic Acid
CAS No. 1217500-78-1
Molecular Formula C14H19BN2O3
Molecular Weight 274.13 g/mol
Synonyms 5-Acrylamido-2-((dimethylamino)methyl)benzeneboronic acid; 2-(Acrylamido)-5-((dimethylamino)methyl)phenylboronic acid; N-[3-Borono-4-[(dimethylamino)methyl]phenyl]acrylamide; B-[2-Acrylamido-5-[(dimethylamino)methyl]phenyl]boronic acid; 5-Acrylamido-2-(N,N-dimethylaminomethyl)phenylboronic acid; Acrylamido-DMAPBA; ADMAPBA
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Quality Control

Every batch of 5-Acrylamido-2-((Dimethylamino)Methyl)Phenylboronic Acid is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality system is designed to meet the stringent requirements of research and development applications, with capabilities to support custom purity grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Purity (HPLC, Area%) ≥ 97.0%
Water Content (KF) ≤ 2.0%
Heavy Metals ≤ 20 ppm
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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