Description

5-Acrylamido-2-(Hydroxymethyl)Phenylboronic Acid is a specialized bifunctional monomer that combines a polymerizable acrylamide group with a reactive phenylboronic acid moiety. This unique structure makes it a critical building block for synthesizing advanced functional polymers and hydrogels with specific binding capabilities. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostics, and advanced materials sectors for applications requiring molecular recognition.

Application

• Biomedical Hydrogels: A key monomer for creating smart, glucose-responsive hydrogels used in controlled drug delivery systems and biosensors.
• Polymer-Supported Reagents: Used to functionalize polymers and resins for solid-phase synthesis and separation technologies in combinatorial chemistry.
• Diagnostic Assays: Serves as a linker or capture agent in the development of diagnostic platforms that target diol-containing molecules like sugars and catechols.
• Surface Modification: Enables the covalent immobilization of biomolecules onto various substrates for creating bioactive surfaces in lab-on-a-chip devices.
• Advanced Material Synthesis: Incorporated into copolymers to impart boronic acid functionality for self-healing materials or environmental sensors.
• Research & Development: A valuable tool in academic and industrial R&D for exploring novel polymer architectures and bio-conjugation strategies.

Basic Information

Product Name	5-Acrylamido-2-(Hydroxymethyl)Phenylboronic Acid
CAS No.	1217500-76-9
Molecular Formula	C10H12BNO4
Molecular Weight	221.02 g/mol
Synonyms	5-Acrylamido-2-(hydroxymethyl)benzeneboronic acid; 2-(Hydroxymethyl)-5-acrylamidophenylboronic acid; N-[3-(Hydroxymethyl)-4-boronophenyl]acrylamide; 5-Acrylamido-2-(hydroxymethyl)phenylboronic acid pinacol ester (related derivative); Acrylamido phenylboronic acid monomer; APBA monomer; Boronic acid acrylamide monomer
EINECS	Contact for details

Quality Control

Every batch of 5-Acrylamido-2-(Hydroxymethyl)Phenylboronic Acid is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, supporting compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.