Description

1-(T-Butoxycarbonyl)Pyrazole-5-Boronic Acid is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in the construction of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those containing pyrazole heterocycles.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid ester coupling partner for the formation of carbon-carbon bonds with aryl/heteroaryl halides.
• Agrochemical Research: Used in the development of new pesticides and herbicides requiring specific heterocyclic architectures.
• Material Science: Potential building block for creating organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Can be employed in the synthesis of molecular probes and activity-based protein profiling reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates.

Basic Information

Product Name	1-(T-Butoxycarbonyl)Pyrazole-5-Boronic Acid
CAS No.	1217500-54-3
Molecular Formula	C8H13BN2O4
Molecular Weight	212.01 g/mol
Synonyms	1-Boc-Pyrazole-5-Boronic Acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylic Acid tert-Butyl Ester; 1-(tert-Butoxycarbonyl)-1H-pyrazole-5-boronic Acid; 1-(Tert-Butoxycarbonyl)-5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Boc-5-Pyrazoleboronic Acid; tert-Butyl 5-borono-1H-pyrazole-1-carboxylate; 1-Boc-Pyrazole-5-Boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 1-(T-Butoxycarbonyl)Pyrazole-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with full specification data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.