Description

2-Benzyloxy-6-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of advanced materials and pharmaceuticals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized to create boronic acid-based probes and sensors for detecting sugars, peroxides, and other biologically relevant analytes.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	2-Benzyloxy-6-Fluorophenylboronic Acid
CAS No.	1217500-53-2
Molecular Formula	C₁₃H₁₂BFO₃
Molecular Weight	246.05 g/mol
Synonyms	(2-(Benzyloxy)-6-fluorophenyl)boronic acid; 2-Fluoro-6-(phenylmethoxy)benzeneboronic acid; 6-Fluoro-2-(phenylmethoxy)benzeneboronic acid; B-[2-(Benzyloxy)-6-fluorophenyl]boronic acid; 2-Benzyloxy-6-fluorobenzeneboronic acid; (6-Fluoro-2-(benzyloxy)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Benzyloxy-6-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.