Description

6-Ethyl-1,6-Dihydropyrimidin-5-Ylboronic Acid is a specialized organoboron compound belonging to the pyrimidine class of heterocyclic building blocks. This chemical is a critical intermediate in modern synthetic chemistry, particularly valued for its role in cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those containing pyrimidine scaffolds for oncology, antiviral, and CNS applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures for bioactivity.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Synthesis: An essential reagent in palladium-catalyzed cross-coupling reactions (Suzuki-Miyaura) to form carbon-carbon bonds, enabling the construction of complex molecular architectures.
• Academic & R&D: Employed in university and corporate research laboratories for methodological development and exploring new chemical spaces.
• Ligand Synthesis: Can be used to create novel bidentate or tridentate ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Ethyl-1,6-Dihydropyrimidin-5-Ylboronic Acid
CAS No.	1217500-51-0
Molecular Formula	C6H11BN2O2
Molecular Weight	153.98 g/mol
Synonyms	5-Borono-6-ethyl-1,6-dihydropyrimidine; (6-Ethyl-1,6-dihydro-5-pyrimidinyl)boronic Acid; 6-Ethyl-1,6-dihydro-5-pyrimidineboronic Acid; 6-Ethyl-5-pyrimidinylboronic Acid; 6-Ethyl-1,6-dihydropyrimidine-5-boronic Acid; 6-Ethyl-1,6-dihydropyrimidin-5-ylboronic Acid Pinacol Ester (protected form); B-(6-Ethyl-1,6-dihydro-5-pyrimidinyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 6-Ethyl-1,6-Dihydropyrimidin-5-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.