Description

Fmoc-Asn(Trt)-Oh-13C4, 15N2 is a high-purity, isotopically labeled derivative of the amino acid asparagine, protected with Fmoc (9-fluorenylmethoxycarbonyl) and Trt (trityl) groups. This compound is essential for advanced research and development in the fields of proteomics and metabolomics, where precise mass spectrometry analysis is required. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and CROs (Contract Research Organizations) specializing in peptide synthesis and biomarker discovery.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of peptides and proteins.
• Isotope-Labeled Peptide Synthesis: A critical building block for the solid-phase synthesis of peptides containing stable isotopes (13C, 15N) for structural and functional studies.
• Metabolic Pathway Tracing: Employed in metabolic flux analysis to track the incorporation of labeled atoms in biological systems.
• Proteomics Research: Facilitates the identification and quantification of proteins in complex biological samples through advanced mass spectrometry techniques.
• Pharmaceutical Development: Supports the development of novel peptide-based therapeutics and diagnostics by providing labeled precursors for pharmacokinetic and pharmacodynamic studies.

Basic Information

Product Name	Fmoc-Asn(Trt)-Oh-13C4, 15N2
CAS No.	1217456-18-2
Molecular Formula	C39H3113C415N2O5
Molecular Weight	~ 677.71 g/mol (for labeled form)
Synonyms	Fmoc-L-asparagine(trityl)-OH-13C4,15N2; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[2-[(triphenylmethyl)amino]-2-oxoethyl]-L-asparagine-13C4,15N2; Fmoc-Asn(Trt)-OH-13C4,15N2; Fmoc-Asparagine(Trt)-13C4,15N2; Isotopically Labeled Fmoc-Asn(Trt)-OH; Stable Isotope Labeled Fmoc-Amino Acid; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-oxo-4-[(triphenylmethyl)amino]butanoic acid-13C4,15N2
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Asn(Trt)-Oh-13C4, 15N2 is manufactured under strict quality systems and undergoes comprehensive analytical testing to ensure identity, purity, and isotopic enrichment. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from NMR, HPLC, and Mass Spectrometry. Our quality commitment aligns with the standards expected for research-grade biochemicals, supporting GLP (Good Laboratory Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 99 atom % 15N
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.