Description

11-Dehydro Thromboxane B3 is a stable metabolite and analog of thromboxane A3, a key eicosanoid signaling molecule derived from eicosapentaenoic acid (EPA). This compound is of significant value as a critical reference standard and analytical tool in biomedical research and pharmaceutical development. It is primarily needed by researchers and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors for studying platelet function, inflammation pathways, and cardiovascular disease mechanisms.

Application

• Biomedical Research Standard: Serves as an essential reference material for the quantification and validation of thromboxane metabolic pathways in experimental models.
• Pharmaceutical R&D: Used in the development and testing of novel anti-thrombotic and anti-inflammatory drug candidates targeting the thromboxane receptor or synthase.
• Clinical Diagnostics: Acts as a calibration standard in advanced analytical techniques like LC-MS/MS for accurately measuring thromboxane metabolites in biological samples (e.g., plasma, urine).
• Metabolomics & Lipidomics: A crucial component in studies mapping the eicosanoid metabolome to understand disease states related to inflammation and coagulation.
• Academic Research: Utilized in university and institutional labs for fundamental studies on the role of ω-3 derived eicosanoids in human physiology and pathology.
• Quality Control & Method Development: Employed by analytical laboratories to develop, optimize, and validate chromatographic and mass spectrometric methods for eicosanoid analysis.

Basic Information

Product Name	11-Dehydro Thromboxane B3
CAS No.	129228-55-3
Molecular Formula	C₂₀H₃₂O₆
Molecular Weight	368.47 g/mol
Synonyms	11-Dehydro-TXB3; 11-Dehydrothromboxane B3; 2,3-Dinor-Thromboxane B3; TXB3 Metabolite II; (5Z,13E)-(15S)-9,11-Dideoxy-15-hydroxy-9-oxoprosta-5,13-dien-1-oic acid; 11-Dehydro-TXB3; DH-TXB3
EINECS	Contact for details

Quality Control

Our 11-Dehydro Thromboxane B3 is produced and handled under strict quality protocols to ensure the high purity and stability required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for reference materials, ensuring reliable and reproducible performance in your laboratory workflows.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, methanol, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.