Description

2-(2,2-Dimethyl-3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. This compound is valued for its role as a key boronic ester reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and process development.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly in medicinal chemistry.
• Pharmaceutical Intermediate: Serves as a key building block in the research and production of active pharmaceutical ingredients (APIs) and candidate drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific boronic ester chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Chemical Biology & Probe Development: Utilized for creating molecular probes and labeled compounds for biochemical and diagnostic applications.
• Process Chemistry & Scale-up: Provides a reliable and consistent starting material for optimizing and scaling synthetic routes from lab to pilot plant.

Basic Information

Product Name	2-(2,2-Dimethyl-3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.	1215867-50-7
Molecular Formula	C₁₅H₂₅BO₃
Molecular Weight	264.17 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-(2,2-dimethyl-3,6-dihydro-2H-pyran-4-yl)-1,3,2-dioxaborolane; 2-(2,2-Dimethyl-3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2,2-dimethyl-3,6-dihydro-2H-pyran-4-yl)boronate; Dihydro-2H-pyran-4-boronic acid pinacol ester; (2,2-Dimethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(2,2-Dimethyl-3,6-dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.