Description

Cyclopropanecarboxylic Acid, 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Ethyl Ester is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing cyclopropane motifs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the cyclopropane ring for bioactive compound design.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis via palladium-catalyzed cross-coupling.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance, flavor, and other high-value fine chemicals.

Basic Information

Item	Detail
Product Name	Cyclopropanecarboxylic Acid, 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Ethyl Ester
CAS No.	1215107-29-1
Molecular Formula	C₁₂H₂₁BO₄
Molecular Weight	240.11 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylic acid ethyl ester; Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylate; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylic Acid Ethyl Ester; Cyclopropanecarboxylic acid, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; BCPE Ester; 2-Boronic acid, cyclopropanecarboxylic acid ethyl ester, pinacol ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Ethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.