Description

2,2-Difluorocyclopentane-1,3-Dione is a high-purity fluorinated diketone building block with significant synthetic utility. This compound is valued for its unique reactivity profile, enabling the introduction of fluorine atoms and the cyclopentanedione scaffold into complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a precursor for advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the difluorinated structure can enhance biological activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocycles and as a versatile reagent in fluorination chemistry.
• Ligand and Catalyst Development: Utilized as a precursor for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2,2-Difluorocyclopentane-1,3-Dione
CAS No.	1215071-21-8
Molecular Formula	C5H4F2O2
Molecular Weight	134.08 g/mol
Synonyms	2,2-Difluorocyclopentane-1,3-dione; 1,3-Cyclopentanedione, 2,2-difluoro-; Difluorocyclopentanedione; 2,2-Difluoro-1,3-cyclopentanedione; 1215071-21-8
EINECS	Contact for details

Quality Control

Our 2,2-Difluorocyclopentane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.