Description

tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenethylcarbamate is a high-purity, protected boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronate ester reagent for forming carbon-carbon bonds under mild conditions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Material Science Research: Intermediate for creating organic electronic materials, ligands for catalysts, and novel polymers.
• Peptide & Protein Modification: Facilitates the site-specific functionalization of biomolecules for bioconjugation and probe development.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenethylcarbamate
CAS No.	1214900-08-9
Molecular Formula	C19H30BNO4
Molecular Weight	347.26 g/mol
Synonyms	Boc-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenethylamine; 2-{3-[(tert-Butoxycarbonyl)amino]phenyl}ethylboronic acid pinacol ester; N-Boc-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethylamine; 3-[(tert-Butoxycarbonylamino)methyl]benzeneboronic acid pinacol ester; tert-Butyl N-[2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl]carbamate; 1214900-08-9; Boc-3-(pinacolboryl)phenethylamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for parameters such as assay, related substances, and residual solvents are available upon request. We adhere to strict quality management protocols to ensure the material meets the high-purity requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.