Description

Methyl 2-([(2-Chloroanilino)Carbonyl]Amino)-3,3-Dimethylbutanoate is a specialized organic compound featuring a unique molecular scaffold combining a tert-leucine ester derivative with a 2-chloroanilino carboxamide moiety. This structure makes it a valuable high-purity building block and intermediate for advanced chemical synthesis. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aniline component.
• Peptidomimetics Research: The tert-leucine ester backbone makes it a valuable scaffold for constructing peptidomimetics and modifying peptide properties in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Employed by fine chemical manufacturers for producing custom-designed molecules for client-specific R&D projects.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.
• Academic & Institutional Research: Used in university and institutional labs for studying reaction mechanisms, catalysis, and structure-activity relationships (SAR).

Basic Information

Product Name	Methyl 2-([(2-Chloroanilino)Carbonyl]Amino)-3,3-Dimethylbutanoate
CAS No.	1214800-15-3
Molecular Formula	C14H19ClN2O3
Molecular Weight	298.77 g/mol
Synonyms	Methyl N-[(2-chlorophenyl)carbamoyl]-3,3-dimethyl-L-norvalinate; Methyl (2S)-2-[[(2-chlorophenyl)carbamoyl]amino]-3,3-dimethylbutanoate; L-tert-Leucine, N-[(2-chlorophenyl)carbonyl]-, methyl ester; 2-Chloro-N-[[(1S)-2-methoxy-1-(2-methyl-2-propanyl)-2-oxoethyl]carbamoyl]benzenamine; Methyl 2-((2-chlorophenylcarbamoyl)amino)-3,3-dimethylbutanoate; tert-Leucine methyl ester derivative with 2-chlorophenyl isocyanate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-([(2-Chloroanilino)Carbonyl]Amino)-3,3-Dimethylbutanoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, assay, impurity profile, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.