Description

2-Chloro-1-(2-Chloro-5-Fluorophenyl)Ethanone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of specialty polymers and liquid crystals where fluorinated aromatic units are required for specific electronic or thermal properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development, such as cross-coupling reactions and nucleophilic substitution studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Chloro-1-(2-Chloro-5-Fluorophenyl)Ethanone
CAS No.	1214391-59-9
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	2-Chloro-1-(2-chloro-5-fluorophenyl)ethan-1-one; 2',5'-Dichloro-2-fluoroacetophenone; 1-(2-Chloro-5-fluorophenyl)-2-chloroethanone; α,2-Dichloro-5-fluoroacetophenone; 2-Chloro-2'-chloro-5'-fluoroacetophenone; (2-Chloro-5-fluorophenyl)chloromethyl ketone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(2-Chloro-5-Fluorophenyl)Ethanone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from laboratory to commercial scale, ensuring reliable supply for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.