Description

1-Chloro-2-(Difluoromethyl)-4-(Trifluoromethyl) Benzene is a high-value, multi-fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both chloro and fluorinated methyl groups, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing components in electronic display and lighting technologies.
• Polymer & Specialty Chemicals: Incorporated into high-performance polymers, surfactants, and coatings to impart oil/water repellency and chemical resistance.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.
• Research & Development: Used in academic and industrial R&D for exploring new fluorinated compounds and their properties.

Basic Information

Product Name	1-Chloro-2-(Difluoromethyl)-4-(Trifluoromethyl) Benzene
CAS No.	1214383-34-2
Molecular Formula	C8H4ClF5
Molecular Weight	230.56 g/mol
Synonyms	2-Chloro-α,α-difluoro-5-(trifluoromethyl)toluene; 1-Chloro-2-(difluoromethyl)-4-(trifluoromethyl)benzene; Benzene, 1-chloro-2-(difluoromethyl)-4-(trifluoromethyl)-; 2-(Difluoromethyl)-1-chloro-4-(trifluoromethyl)benzene; 4-Chloro-3-(trifluoromethyl)benzylidene difluoride
EINECS	Contact for details

Quality Control

Our production of 1-Chloro-2-(Difluoromethyl)-4-(Trifluoromethyl) Benzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment. We support our partners in meeting their regulatory and compliance needs for advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.