Description

1-(2-Fluoro-6-Nitrophenyl)Ethanone is a specialized aromatic ketone building block featuring both fluoro and nitro substituents, which are critical for directing subsequent chemical transformations. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the nitro and fluoro groups contribute to biological activity.
• Material Science Research: Acts as a building block for creating advanced organic materials, such as liquid crystals or organic semiconductors.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments, leveraging the nitro group's electron-withdrawing properties.
• Cross-Coupling Reactions: The halogenated aromatic ring makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Organic Synthesis Research: A versatile reagent for academic and industrial research into new fluorination methodologies and nitro group transformations.

Basic Information

Product Name	1-(2-Fluoro-6-Nitrophenyl)Ethanone
CAS No.	1214377-22-6
Molecular Formula	C8H6FNO3
Molecular Weight	183.14 g/mol
Synonyms	2'-Fluoro-6'-nitroacetophenone; 1-Acetyl-2-fluoro-6-nitrobenzene; 2-Fluoro-6-nitroacetophenone; Ethanone, 1-(2-fluoro-6-nitrophenyl)-; 2-Fluoro-6-nitroacetylbenzene; 1-(2-Fluoro-6-nitrophenyl)ethan-1-one; α-Fluoro-α'-nitroacetophenone (isomer specific)
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-6-Nitrophenyl)Ethanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.