Description

4-Fluoro-2-Methoxybenzene-1-Sulfonyl Chloride is a high-purity, versatile sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its value lies in its reactive sulfonyl chloride group, which enables efficient introduction of the sulfonamide moiety, a key functional group in many active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly for creating sulfonamide-based drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides with sulfonamide backbones.
• Chemical Research & Development: Serves as a versatile reagent for introducing sulfonyl groups in complex molecule construction and medicinal chemistry projects.
• Material Science: Potential use in the synthesis of specialty polymers and functional materials requiring sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates for client-specific applications.

Basic Information

Item	Detail
Product Name	4-Fluoro-2-Methoxybenzene-1-Sulfonyl Chloride
CAS No.	1214377-19-1
Molecular Formula	C7H6ClFO3S
Molecular Weight	224.64 g/mol
Synonyms	2-Methoxy-4-fluorobenzenesulfonyl chloride; 4-Fluoro-2-methoxybenzenesulfonyl chloride; 1-(Chlorosulfonyl)-4-fluoro-2-methoxybenzene; 4-Fluoro-2-methoxy-1-sulfonyl chloride benzene; 4-Fluoro-o-anisylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxybenzene-1-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically exceeding 97% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.