Description

2-Chloro-1-(2-Chloro-3-Fluorophenyl)Ethanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring strategically placed chlorine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a versatile precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl moiety.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic structure.
• Chemical Biology Probes: Employed as a building block for creating fluorescent tags, photoaffinity labels, and other molecular tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in bespoke synthesis projects for clients.

Basic Information

Product Name	2-Chloro-1-(2-Chloro-3-Fluorophenyl)Ethanone
CAS No.	1214362-75-0
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	1-(2-Chloro-3-fluorophenyl)-2-chloroethanone; 2-Chloro-1-(2-chloro-3-fluorophenyl)ethan-1-one; 2',3'-Dichloro-2-fluoroacetophenone; α,2-Dichloro-3-fluoroacetophenone; 2-Chloro-2'-chloro-3'-fluoroacetophenone; (2-Chloro-3-fluorophenyl)(chloro)methanone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(2-Chloro-3-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.