Description

3'-Fluoro-2'-Nitroacetophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both electron-withdrawing nitro and fluoro substituents, makes it a valuable precursor for constructing complex heterocyclic systems and functionalized intermediates. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with tailored electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development, catalysis studies, and the creation of complex molecular libraries.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal complexes used in catalytic processes.

Basic Information

Product Name	3'-Fluoro-2'-Nitroacetophenone
CAS No.	1214346-37-8
Molecular Formula	C8H6FNO3
Molecular Weight	183.14 g/mol
Synonyms	1-(3-Fluoro-2-nitrophenyl)ethan-1-one; 3-Fluoro-2-nitroacetophenone; 2-Nitro-3-fluoroacetophenone; 3'-Fluoro-2'-nitroacetophenone; Ethanone, 1-(3-fluoro-2-nitrophenyl)-; 1-Acetyl-3-fluoro-2-nitrobenzene
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-2'-Nitroacetophenone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.