Description

2-(Difluoromethyl)-1,3,5-Trifluorobenzene is a highly fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a difluoromethyl group on a perfluorinated benzene ring, makes it a valuable precursor for creating complex molecules with tailored electronic and physical properties. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Serves as a critical building block for the creation of next-generation herbicides, fungicides, and insecticides, where fluorine atoms enhance product efficacy and environmental profile.
• Material Science Precursor: Used in the synthesis of specialty polymers, liquid crystals, and electronic materials that benefit from the introduction of fluorinated aromatic units.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D settings to explore new fluorination methodologies and catalytic transformations of polyfluorinated arenes.
• Ligand and Functional Molecule Development: Acts as a starting material for synthesizing complex ligands for catalysis or functional molecules with specific surface properties.

Basic Information

Product Name	2-(Difluoromethyl)-1,3,5-Trifluorobenzene
CAS No.	1214338-85-8
Molecular Formula	C7H3F5
Molecular Weight	182.09 g/mol
Synonyms	1,3,5-Trifluoro-2-(difluoromethyl)benzene; (Difluoromethyl)-1,3,5-trifluorobenzene; 2-(Difluoromethyl)-1,3,5-trifluorobenzene; 1,3,5-Trifluoro-2-difluoromethylbenzene; α,α-Difluoro-2,4,6-trifluorotoluene
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethyl)-1,3,5-Trifluorobenzene is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. For long-term storage, maintaining the container at temperatures between 2°C and 8°C is recommended to ensure optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.