Description

1-(3-Chloro-2-Fluorophenyl)Propan-1-One is a high-purity fluorinated aromatic ketone building block essential for advanced organic synthesis. This compound is valued for its precise molecular structure, which serves as a critical intermediate in the development of complex active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional organic materials.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Used in research laboratories for methodological studies in cross-coupling reactions and fluorination chemistry.

Basic Information

Product Name	1-(3-Chloro-2-Fluorophenyl)Propan-1-One
CAS No.	1214323-04-2
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	3'-Chloro-2'-fluoropropiophenone; 1-Propanone, 1-(3-chloro-2-fluorophenyl)-; 3-Chloro-2-fluoropropiophenone; (3-Chloro-2-fluorophenyl)propan-1-one; 2-Fluoro-3-chloropropiophenone; 1-(3-Chloro-2-fluorophenyl)propanone; Propiophenone, 3'-chloro-2'-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Chloro-2-Fluorophenyl)Propan-1-One is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets high-purity specifications suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.