Description

6-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in the protected boronic ester functional group, which is essential for modern cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials. We supply this key intermediate with a focus on batch-to-batch consistency and reliable global logistics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boron-containing coupling partner for constructing biaryl and heterobiaryl systems central to many drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science & OLED Development: Employed as a building block for creating organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in OLEDs.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	6-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1214242-09-7
Molecular Formula	C12H19BN2O2
Molecular Weight	234.11 g/mol
Synonyms	2-Amino-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methylpyridin-2-amine; 6-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 2-Pyridinamine, 6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methylpyridin-2-amine; 6-Methyl-4-(pinacolatoboron)pyridin-2-amine; 2-Amino-6-methyl-4-pyridineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H and 13C), and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.