Description

(R)-B-Amino-3-Fluoro-Benzeneethanol is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its enantiomeric purity and the strategic fluorine substitution, which are critical for developing active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. This compound is essential for research and production facilities in the pharmaceutical and fine chemical industries, particularly those focused on synthesizing novel therapeutics and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure APIs, especially for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Research: Used in developing advanced, fluorine-containing pesticides and herbicides where the chiral center influences biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand for chiral catalysts used in stereoselective synthesis.
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) in medicinal chemistry due to the fluorine atom.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing complex, high-value specialty chemicals.

Basic Information

Product Name	(R)-B-Amino-3-Fluoro-Benzeneethanol
CAS No.	1213968-04-7
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	(R)-2-Amino-1-(3-fluorophenyl)ethanol; (R)-1-(3-Fluorophenyl)-2-aminoethanol; (R)-3-Fluoro-β-amino-phenethyl alcohol; (R)-(-)-2-Amino-1-(3-fluorophenyl)ethanol; (R)-β-Amino-3-fluorobenzeneethanol; (R)-3-Fluoro-β-amino-phenylethanol; (R)-1-(3-Fluorophenyl)-2-aminoethan-1-ol
EINECS	Contact for details

Quality Control

Our (R)-B-Amino-3-Fluoro-Benzeneethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and impurity profile. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.