Description

(3S)-3-[4-(Trifluoromethyl)Phenyl]Morpholine CAS NO 1213924-94-7 is a high-purity, chiral morpholine derivative characterized by a trifluoromethylphenyl substituent. This compound is a critical pharmaceutical intermediate and building block for the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams requiring enantiomerically pure scaffolds for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, essential for producing enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or additive for specialty polymers with unique optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	(3S)-3-[4-(Trifluoromethyl)Phenyl]Morpholine
CAS No.	1213924-94-7
Molecular Formula	C11H12F3NO
Molecular Weight	231.21 g/mol
Synonyms	(S)-3-(4-(Trifluoromethyl)phenyl)morpholine; (3S)-3-[4-(Trifluoromethyl)phenyl]morpholine; (S)-3-(4-Trifluoromethylphenyl)morpholine; 4-(Trifluoromethyl)phenyl-morpholine, (S)-; Morpholine, 3-[4-(trifluoromethyl)phenyl]-, (3S)-; (S)-3-(p-Trifluoromethylphenyl)morpholine
EINECS	Contact for details

Quality Control

Our (3S)-3-[4-(Trifluoromethyl)Phenyl]Morpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess and NMR for structural confirmation, to ensure compliance with exacting standards for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.