Description

(S)-2-(2-Fluoro-3-Methoxy-Phenyl)-Pyrrolidine is a high-purity chiral building block and intermediate of significant importance in modern pharmaceutical research and development. Its value lies in its specific stereochemistry and functional group arrangement, which are critical for creating targeted biological activity in drug candidates. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, or insecticides where specific chirality impacts biological efficacy.
• Process Chemistry: Investigated for scalable synthesis routes in the pilot plant and commercial manufacturing of complex molecules.
• Reference Standard: Used as an analytical standard for quality control and method development in regulatory submissions.

Basic Information

Product Name	(S)-2-(2-Fluoro-3-Methoxy-Phenyl)-Pyrrolidine
CAS No.	1213866-20-6
Molecular Formula	C11H14FNO
Molecular Weight	195.23 g/mol
Synonyms	(S)-2-(2-Fluoro-3-methoxyphenyl)pyrrolidine; (2S)-2-(2-Fluoro-3-methoxyphenyl)pyrrolidine; (S)-2-(2-Fluoro-3-methoxyphenyl)pyrrolidine; 1213866-20-6; Pyrrolidine, 2-(2-fluoro-3-methoxyphenyl)-, (2S)-; (S)-2-(2-Fluoro-3-Methoxy-Phenyl)-Pyrrolidine; (S)-2-(2-Fluoro-3-Methoxyphenyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-2-(2-Fluoro-3-Methoxy-Phenyl)-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.