Description

(2S)-2-(2-Fluoro-5-Methylphenyl)Pyrrolidine is a chiral pyrrolidine derivative, a high-value building block in modern organic synthesis. Its core value lies in its defined stereochemistry and functionalized aromatic ring, which are critical for imparting specific biological activity and physical properties in advanced molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, especially for neurological targets.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the fluorinated phenylpyrrolidine scaffold can enhance activity and selectivity.
• Ligand Synthesis: Serves as a starting material for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and enzyme functions.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with unique optical or electronic properties.
• Process Chemistry Development: Used in scaling up synthetic routes for complex molecules in pilot plants and commercial manufacturing.

Basic Information

Product Name	(2S)-2-(2-Fluoro-5-Methylphenyl)Pyrrolidine
CAS No.	1213485-64-3
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	(S)-2-(2-Fluoro-5-methylphenyl)pyrrolidine; (2S)-2-(2-Fluoro-5-methylphenyl)-1-pyrrolidine; 2-(2-Fluoro-5-methylphenyl)pyrrolidine, (2S)-; (S)-2-(2-Fluoro-5-methyl-1-phenylene)pyrrolidine; 1213485-64-3; (S)-2-(2-Fluoro-5-methylphenyl)pyrrolidine; Pyrrolidine, 2-(2-fluoro-5-methylphenyl)-, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2-(2-Fluoro-5-Methylphenyl)Pyrrolidine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.