Description

(R)-1-(2,2-Difluoro-Benzo[1,3]Dioxol-4-Yl)-Ethylamine is a chiral amine building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules with high stereochemical purity, which is critical for developing active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel, high-value compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure herbicides, fungicides, and insecticides for enhanced efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Manufacturing: Employed in the synthesis of complex, high-value specialty chemicals for electronics, materials science, and flavor/fragrance industries.
• Academic and Contract Research: A valuable reagent for methodological studies in organic chemistry and for contract research organizations (CROs) serving the life sciences sector.

Basic Information

Item	Details
Product Name	(R)-1-(2,2-Difluoro-Benzo[1,3]Dioxol-4-Yl)-Ethylamine
CAS No.	1213203-92-9
Molecular Formula	C9H9F2NO2
Molecular Weight	201.17 g/mol
Synonyms	(R)-1-(2,2-Difluoro-1,3-benzodioxol-4-yl)ethan-1-amine; (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-4-yl)ethanamine; (R)-4-(1-Aminoethyl)-2,2-difluoro-1,3-benzodioxole; (R)-2,2-Difluoro-4-(1-aminoethyl)-1,3-benzodioxole; (R)-1-(2,2-Difluoro-1,3-benzodioxol-5-yl)ethylamine (alternative numbering); (R)-α-Methyl-2,2-difluorobenzodioxole-4-ethanamine
EINECS	Contact for details

Quality Control

Our (R)-1-(2,2-Difluoro-Benzo[1,3]Dioxol-4-Yl)-Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.