Description

(3S)-3-(2-Fluorophenyl)Morpholine is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. Its core value proposition lies in its defined stereochemistry and fluorinated aromatic structure, which are critical for modulating the biological activity and pharmacokinetic properties of advanced drug candidates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those working on central nervous system (CNS) agents, enzyme inhibitors, and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the design of molecular probes to investigate biological pathways.
• Material Science Research: Potential monomer or additive for specialty polymers and advanced materials requiring specific fluorinated motifs.

Basic Information

Product Name	(3S)-3-(2-Fluorophenyl)Morpholine
CAS No.	1212960-31-0
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	(S)-3-(2-Fluorophenyl)morpholine; (3S)-3-(2-Fluorophenyl)-morpholine; Morpholine, 3-(2-fluorophenyl)-, (3S)-; (S)-2-Fluorophenylmorpholine; (S)-3-(o-Fluorophenyl)morpholine; (S)-(-)-3-(2-Fluorophenyl)morpholine; (3S)-3-(2-Fluoro-phenyl)-morpholine
EINECS	Contact for details

Quality Control

Our (3S)-3-(2-Fluorophenyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, NMR, and GC/HPLC for chemical purity, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.