Description

(S)-3-Formyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester is a high-value chiral building block and protected amino acid derivative essential for modern pharmaceutical synthesis. Its core value lies in providing a stereochemically defined, functionalized pyrrolidine scaffold that is readily incorporated into complex target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, especially those targeting neurological and psychiatric disorders.
• Protease Inhibitor Development: Used as a core structural element in the research and production of inhibitors for various proteolytic enzymes.
• Peptidomimetics: Serves as a constrained, non-natural amino acid analog for creating stable peptide-like molecules with enhanced pharmacological properties.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective chemical reactions to construct molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Utilized in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Chemical Biology Probes: Incorporated into molecular tools for studying biological processes and protein function.

Basic Information

Item	Detail
Product Name	(S)-3-Formyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester
CAS No.	1212307-91-9
Molecular Formula	C13H15NO3
Molecular Weight	233.26 g/mol
Synonyms	(S)-1-(Benzyloxycarbonyl)-3-formylpyrrolidine; (S)-1-Cbz-3-formylpyrrolidine; (S)-N-Cbz-3-formylpyrrolidine; (S)-3-Formyl-1-[(phenylmethoxy)carbonyl]pyrrolidine; Benzyl (S)-3-formylpyrrolidine-1-carboxylate; (S)-3-Formylpyrrolidine-1-carboxylic acid benzyl ester; 1-CBZ-3-FORMYL-(S)-PYRROLIDINE; (S)-1-Carbobenzyloxy-3-formylpyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-3-Formyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.