Description

Diexo-3-Amino-7-Oxa-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique constrained bicyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules, offering a rigid scaffold for drug discovery. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in developing new therapeutics, particularly in the areas of neurology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates and novel APIs.
• Protease Inhibitor Research: Used in the development of inhibitors targeting specific enzymes due to its constrained amino acid-like structure.
• Peptidomimetics: Serves as a core scaffold for designing peptide mimics with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical transformations.
• Medicinal Chemistry: Integral for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation Chemistry: The amino and ester functional groups allow for selective modification and linker attachment in biopharmaceutical development.

Basic Information

Product Name	Diexo-3-Amino-7-Oxa-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester
CAS No.	1212263-59-6
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	(1R,2S,4S)-3-Amino-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester; Ethyl (1R,2S,4S)-3-amino-7-oxabicyclo[2.2.1]heptane-2-carboxylate; exo-3-Amino-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester; 7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-, ethyl ester, (1R,2S,4S)-; Bicyclic amino acid ester; 1212263-59-6
EINECS	Contact for details

Quality Control

Our Diexo-3-Amino-7-Oxa-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.