Description

2,2,6,6-Tetramethyl-Tetrahydro-2H-Pyran-4-Carbaldehyde is a specialized aldehyde derivative of a tetramethyl-substituted tetrahydropyran, serving as a valuable synthetic intermediate in advanced organic chemistry. Its unique sterically hindered structure makes it a critical building block for the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This high-purity compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for complex, sterically demanding molecular architectures.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its aldehyde functionality allows for further derivatization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high-purity, structurally defined intermediates.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for exploring new chemical reactions.

Basic Information

Product Name	2,2,6,6-Tetramethyl-Tetrahydro-2H-Pyran-4-Carbaldehyde
CAS No.	1212021-33-4
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	2,2,6,6-Tetramethyl-4-oxotetrahydropyran; 2,2,6,6-Tetramethyltetrahydro-2H-pyran-4-carboxaldehyde; 4-Formyl-2,2,6,6-tetramethyltetrahydropyran; Tetramethyltetrahydropyran-4-carbaldehyde; 2,2,6,6-Tetramethyl-4-pyrancarboxaldehyde; TMTHP-4-Carbaldehyde
EINECS	Contact for details

Quality Control

Our 2,2,6,6-Tetramethyl-Tetrahydro-2H-Pyran-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Due to its sensitivity to oxidation, the container should be kept sealed and purged with inert gas after each use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.