Description

4-Fluoro-1H-Pyrazol-3-Amine CAS NO 1211540-17-8 is a high-value fluorinated pyrazole derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate a fluorinated heterocyclic amine moiety into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in creating novel herbicides, fungicides, and insecticides where the fluoropyrazole core enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for nitrogen-donor ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	4-Fluoro-1H-Pyrazol-3-Amine
CAS No.	1211540-17-8
Molecular Formula	C3H4FN3
Molecular Weight	101.08 g/mol
Synonyms	3-Amino-4-fluoropyrazole; 4-Fluoropyrazol-3-amine; 4-Fluoro-1H-pyrazol-3-ylamine; 4-Fluoro-3-pyrazolamine; 4-Fluoro-1H-pyrazol-3-amine; 4-Fluoro-3-aminopyrazole; 1H-Pyrazol-3-amine, 4-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1H-Pyrazol-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.