Description

5-(Trifluoromethoxy)Isoindoline is a high-value, fluorinated organic building block characterized by its unique isoindoline core and trifluoromethoxy substituent. This compound is essential for medicinal chemistry and advanced materials research, where its structure imparts desirable properties such as metabolic stability and enhanced lipophilicity. It is primarily needed by pharmaceutical R&D teams and agrochemical manufacturers for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for developing new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the stability of the CF3O group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and material science.
• Functional Material Research: Incorporated into polymers and advanced organic frameworks to modify electronic properties and stability.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	5-(Trifluoromethoxy)Isoindoline
CAS No.	1211532-42-1
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	5-(Trifluoromethoxy)-2,3-dihydro-1H-isoindole; Isoindoline, 5-(trifluoromethoxy)-; 1H-Isoindole, 2,3-dihydro-5-(trifluoromethoxy)-; 5-(Trifluoromethoxy)isoindoline; 5-Trifluoromethoxyisoindoline
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethoxy)Isoindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.