Description

2-Methoxy-5-(Pentafluorosulfur)Benzylamine is a specialized fluorinated aromatic amine building block. This compound is valued for its unique combination of a benzylamine moiety and a highly electronegative pentafluorosulfur (SF5) group, which imparts significant lipophilicity and metabolic stability. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly where enhanced bioavailability and resistance to degradation are critical.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in areas targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the SF5 group for improved pest selectivity and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and organic semiconductors.
• Advanced Polymer Chemistry: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Positron Emission Tomography (PET) Tracers: Potential building block for creating fluorine-18 labeled radiopharmaceuticals for medical imaging.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and probe development due to the amine functionality.

Basic Information

Product Name	2-Methoxy-5-(Pentafluorosulfur)Benzylamine
CAS No.	1211516-76-5
Molecular Formula	C8H8F5NOS
Molecular Weight	261.21 g/mol
Synonyms	5-(Pentafluoro-λ6-sulfanyl)-2-methoxybenzenemethanamine; (2-Methoxy-5-(pentafluorosulfanyl)phenyl)methanamine; 2-Methoxy-5-(SF5)benzylamine; α-Amino-2-methoxy-5-pentafluorosulfanyltoluene; Benzenemethanamine, 2-methoxy-5-(pentafluorosulfanyl)-; 2-Methoxy-5-pentafluorosulfanylbenzylamine
EINECS	Contact for details

Quality Control

Our production of 2-Methoxy-5-(Pentafluorosulfur)Benzylamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.