Description

2,4-Difluoro-3-Bromoacetophenone is a high-purity fluorinated and brominated aromatic ketone building block. This compound is valued for its unique reactivity profile, serving as a versatile intermediate in the synthesis of complex organic molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring difluorinated and brominated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine and bromine atoms can enhance biological activity and environmental stability.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated structure.
• Chemical Research & Development: Serves as a versatile building block for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions in academic and industrial labs.
• Fine Chemical Production: Utilized in the custom synthesis of complex fluorinated and brominated compounds for various high-value industrial applications.

Basic Information

Product Name	2,4-Difluoro-3-Bromoacetophenone
CAS No.	1210824-63-7
Molecular Formula	C8H5BrF2O
Molecular Weight	235.03 g/mol
Synonyms	1-(3-Bromo-2,4-difluorophenyl)ethanone; 3'-Bromo-2',4'-difluoroacetophenone; 2,4-Difluoro-3-bromoacetophenone; 3-Bromo-2,4-difluoroacetophenone; Ethanone, 1-(3-bromo-2,4-difluorophenyl)-; 1-(3-Bromo-2,4-difluorophenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Bromoacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.